Hossein Kazemi is one of the pioneers of modern Iranian painting, which combines the oriental view with universal styles. From 1942 to 1945, he studied painting at the university of Tehran, and by the time of graduating, he exhibited several of his paintings in the "Exhibition of Fine Arts of Iran"; organized by the Association of Cultural Relations between Iran and the Soviet Union. Between 1947 and 1949, he held several exhibitions of his works. In 1950 he founded the apadana hall in collaboration with Mahmoud Javadipour, and held several exhibitions there. In 1953, he went to Paris and entered the School of Fine Arts. After returning to Tehran in 1960, he held an exhibition of his works in Reza Abbasi Hall.

For a while, he was the director of the Tehran Boys' Fine Arts Conservatory and was in charge of the Decorative Arts Academy. Hossein Kazemi received a gold medal in the first and second biennials of Tehran in 1958 and 1960. Kazemi spent the rest of his life in France.

A period of Kazemi's works shows realism in the Impressionist style. Interest in abstraction is an approach that is becoming more and more prominent in Kazemi's works and is perfected in his later works. The theme of contradiction, as well as the opposition and unity of contrasting elements, is his favorite theme. This element is especially evident in the semi-abstract collection of "Flowers and Stones".

Jalal Sattari writes about the collection of flowers and stones of Kazemi: "These stones and flowers are the double conscience of human beings who reach perfection only in the light of love, that is, they become harmonious, integrated and fertile."