Hossein Kazemi is one of the pioneers of modern Iranian painting, blending oriental perspectives with universal styles.

From 1942 to 1945, he studied painting at the University of Tehran. By the time of his graduation, he had already exhibited several of his paintings in the "Exhibition of Fine Arts of Iran," organized by the Association of Cultural Relations between Iran and the Soviet Union. Between 1947 and 1949, Kazemi held several exhibitions of his works. In 1950, he founded the Apadana Hall in collaboration with Mahmoud Javadipour and held numerous exhibitions there. In 1953, he went to Paris to study at the School of Fine Arts. Upon his return to Tehran in 1960, he held an exhibition of his works at the Reza Abbasi Hall.

Kazemi served as the director of the Tehran Boys' Fine Arts Conservatory and was in charge of the Decorative Arts Academy. He received gold medals at the first and second Tehran Biennials in 1958 and 1960. Later in life, Kazemi moved to France, where he continued his artistic endeavors.

A period of Kazemi's works showcases realism in the Impressionist style. His interest in abstraction became increasingly prominent and was perfected in his later works. The theme of contradiction, as well as the opposition and unity of contrasting elements, is a recurring motif in his art. This is particularly evident in his semi-abstract collection, "Flowers and Stones."

Jalal Sattari writes about Kazemi's "Flowers and Stones" collection: "These stones and flowers are the dual conscience of human beings, achieving perfection only in the light of love, where they become harmonious, integrated, and fertile."