Ali Shirazi is one of the distinguished calligraphers of Iran. The Shirazi calligraphy community considers the calligrapher and calligrapher to be unique. He combined his mastery of Nasta'liq with painting and entered the art jirga called calligraphy.

His interest in calligraphy began due to his blood heritage and childhood events. "I had a special autograph as a child when I had to write homework. I had to write the homework in pencil at that time, but exceptionally I had written in autograph. Maybe it made me write better, and because it was bolder, my work was more visible than the other kids. My teacher then showed my homework to the children and encouraged me. "My grandfather had good handwriting in the village ... My relatives used to say that my handwriting was as good as my grandfather's." This interest was tested experimentally during his studies, and Shirazi's handwriting gradually became more pleasant; in high school, his teacher asked him to write a role model for his classmates on the blackboard. In 1974, he went to MoinolKetab Isfahani and, for the first time, was trained professionally in this art. Over the years, he opted for the "Negarestan Khat" book by Seyyed Hassan Mirkhani and practiced all its pages. After that, he became acquainted with Gholam Hossein Amirkhani's calligraphy through the pieces published in the magazine "Honar va Mardom" and became interested in his style and used it as a model for his work. From 1958 and 1959, he had a direct relationship with Amirkhani until he left for Tehran in 1988, and this relationship continued. Shirazi devoted several years to imitating Amirkhani's pen. He later became a member of the Supreme Council of the Iranian Calligraphers Association. Ali Shirazi has had more than 19 solo exhibitions inside and outside Iran. Many of his artworks are kept in prestigious art centers in Dubai, Qatar, and Iran.

Kaveh Teymouri writes about the influence of the Shirazi script: The method that was formed from the school of Master Ali Akbar Kaveh through the life of Master Nasrollah Moin, its main cylinder, and then enriched with the teachings of calligraphers of Isfahan and flourished in the presence of Master Gholam Hossein Amirkhani. At the same time, Shirazi's pen and his dynamic mind were inspired by ancient lines, especially the boldness and drive of Mirza Ghalam Reza Esfahani (1866-1925) and the softness and fluidity of Mir Hossein Tork (1856-1918) and the smoothness, elegance, and strength of the Mir Emad Achieved in the art of calligraphy, which is now a valuable center of gravity for contemporary Iranian calligraphy. "At the same time, in terms of composition, he is still attached to Amirkhani's magical compositions in a variety of letters and words, and his ability to write acronyms in readability." Shirazi is highly skilled in calligraphy with large pens, two, three centimeters wide, and higher. He is also faithful to the basics of calligraphy in his paintings. He sorts his large lines into symmetrical circular and square forms. Sometimes asymmetric forms are used for this purpose, in which the flow of lines enters obliquely on one side and exits on the other, accompanied by the repetition of this motif on the sides.

  Ali Shirazi's first appearance in the auctions dates back to November 2011 at the Christie's Auction House. As of March 2021, his artworks have been in 33 domestic and foreign auctions. And 85% of his artworks have been sold in international auctions. His most expensive work until 2021 was hammered at the Christie's Auction House for $ 60,000 on April 2012.