Mansoureh Hosseini is a modernist painter and one of the first iranian artists who used calligraphy in abstract painting. Mansoureh Hosseini graduated from the Faculty of Fine Arts in the University of Tehran (1945-1949) and in the same year her works were exhibited for the first time in the Iranian-British Cultural Association. In 1954 she went to Italy to continue her education and studied at the Academy of Fine Arts in Rome. Her works got to the Venice and Tehran Biennials and in 1958 she won an award in the first Tehran Biennial. Since then, her works have been showcased in many group and solo exhibitions in Iran and other countries. Tehran Museum of Contemporary Art held an exhibition of her works called "Pioneers of Modern Iranian Art: Mansoureh Hosseini" in 2004. Mansoureh Hosseini has been writing critics in the "Ettela'at newspaper" since 1967 under the Alias "Dr. Assad". She has also published a story book called "Dirty Boot". Mansoureh Hosseini's first appearance at the auctions dates back to February 2007 at the Christie's Auction House. 

Her approach toward expressive presentation in painting is reflected in her calligraphic paintings and sometimes in flowers and portraits. Her first paintings of flowers date back to the early 60s and she exhibited a collection of them for the first time in 1965 called "Two flowers in thirty screens".

Mansoureh Hosseini said about the use of calligraphy in her paintings, especially the Kufic calligraphy: "What I have inspired from the Kufic calligraphy is not the lines themselves or their complete decalcomania. My tendency was that their mobility, repetitiveness, silence, composition, the colors of their frame could take a posture and show calmness or escape from horrifying news and fade into the darkness, or float in the dusty lights, expressing some kind of praying moment or show a sorrowful dance."